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. 2019 Feb 22;24:15. doi: 10.1186/s11658-019-0142-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Honokiol inhibits serum inflammatory cytokines in septic mice. Serum levels of TNF-α (a), IL-6 (b) and IL-1β (c) were detected using mouse bioactive ELISA assay in CLP-induced septic mice. Values are expressed as mean ± SEM, n = 10 in Con or H + CLP group and n = 8 in CLP or L + CLP group. ^*** P < 0.001, versus control group; ^## P < 0.01 and ^### P < 0.001 versus CLP single treatment group