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. 2019 Feb 9;36(5):802–814. doi: 10.1089/neu.2018.5810

FIG. 2.

FIG. 2.

Traumatic brain injury (TBI) decreases wakefulness and increases non-rapid eye movement sleep during the dark period in C57BL/6J mice but not in hypocretin knockout mice. electroencephalography (EEG) and home cage activity recordings were obtained from four groups of mice: sham surgery C57BL/6J mice (n = 8); TBI surgery C57BL/6J mice (n = 9); sham surgery hypocretin knockout (HCRT KO) mice (n = 8); and TBI surgery HCRT KO mice (n = 8). Values are means (± standard error of the mean) percent of time spent in wakefulness (WAKE), non-rapid eye movement (NREM) sleep, and rapid eye movement (REM) sleep during the 12 h dark periods at baseline, 3, 7, 15, and 30 days post-surgery. * indicates a statistically significant difference (p < 0.05) between genotypes (C57BL/6J vs. HCRT KO) within the same condition. # indicates a statistically significant difference (p < 0.05) between conditions (sham vs. TBI) with the same genotype.