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. 2019 Feb 9;36(5):815–833. doi: 10.1089/neu.2018.5736

Table 3.

Arterial Blood Gases and Chemistry in Experimental Phase 2

  Pre-injury Post-injury Sacrifice
Base excess (BEEcf) (mmol/L)      
 Group 1 5.25 ± 0.63a -2.75 ± 2.84b 0.00 ± 2.00a,b
 Group 2 4.50 ± 1.32a 2.25 ± 1.31b 1.67 ± 0.67a,b
 Group 3 4.00 ± 0.84a -5.80 ± 4.33b -3.75 ± 6.55a,b
 Sham 7.00 ± 1.00a 3.00 ± 2.52b 6.00 ± 0.00a,b
Total CO2 (mmol/L)      
 Group 1 29.5 ± 0.65a 23.7 ± 2.59b 27.0 ± 2.00a,b
 Group 2 27.7 ± 1.70a 25.5 ± 1.26b 28.0 ± 1.53a,b
 Group 3 28.8 ± 1.07a 22.0 ± 2.86b 28.0 ± 1.53a,b
 Sham 32.5 ± 1.50a 28.7 ± 1.45b 31.0 ± 0.00a,b
Oxygen saturation (%)      
 Group 1 99.0 ± 0.58a 93.2 ± 2.81a 94.5 ± 2.50a,b
 Group 2 98.0 ± 0.9a 96.7 ± 1.11a 98.5 ± 1.50a
 Group 3 63.0 ± 19.4b* 70.2 ± 19.6b* 68.8 ± 16.1b*
 Sham 81.5 ± 4.50a,b 75.7 ± 6.84a,b 95.0 ± 0.00a,b
Sodium (mmol/L)      
 Group 1 137 ± 0.75a 139 ± 0.50b,c 141 ± 0.88b,c
 Group 2 137 ± 2.33a 141 ± 0.63b,c 141 ± 0.58b,c
 Group 3 137 ± 0.75a 141 ± 0.89b,c 143 ± 1.80b,c
 Sham 138 ± 1.00a 142 ± 2.96b,c 139 ± 0.00b,c
Glucose (mg/dL)      
 Group 1 109 ± 14.2a 162 ± 3.90b 136 ± 17.5a,b
 Group 2 126 ± 24.8a 149 ± 11.4b 118 ± 3.00a,b
 Group 3 121 ± 5.79a 160 ± 20.4b 114 ± 17.1a,b
 Sham 74.5 ± 9.5a 104 ± 2.89b 113 ± 0.00a,b

Data are expressed as means ± SEM. Means with different letters differ, p < 0.05. Group 1, n = 5: focal injuries + apnea, hypoventilation; Group 2, n = 4: focal injuries + seizures; Group 3, n = 7: focal injuries + apnea, hypoventilation + seizures. *Treatment 1 tended to be different than treatment 3, p = 0.053.

BEEcf, Base excess in the extracellular fluid compartment; SEM, standard error of the mean.