. 2019 Feb 9;36(5):815–833. doi: 10.1089/neu.2018.5736

Table 8.

Arterial Blood Gases and Chemistry in Experimental Phase 3 of Model Development

	Pre-injury	4–7 h post-injury	8–16 h post-injury	Sacrifice
pH
Injured	7.52 ± 0.03^a	7.39 ± 0.03^b	7.43 ± 0.02	7.43 ± 0.02^a,b
Sham	7.57 ± 0.037^a,b	7.53 ± 0.03^a,b		7.4 ± 0.06^a,b
Partial pressure of carbon dioxide (mm Hg)
Injured	33.6 ± 2.01^a	34.9 ± 3.01^a,b	35.7 ± 4.47	42.8 ± 2.50^b
Sham	32.8 ± 2.25^a	33.5 ± 1.1^a		53.2 ± 5.6^b
Bicarbonate (mmol/L)
Injured	27.4 ± 0.89^a	22.56 ± 2.59^b	23.7 ± 2.51	28.6 ± 0.67^a
Sham	29.85 ± 0.55^a,b	28.25 ± 0.95^a,b		32.6 ± 0.6^a,b
Total carbon dioxide (mmol/L)
Injured	28.43 ± 0.896^a	23.7 ± 2.68^b	24.8 ± 2.56	30 ± 0.76^a
Sham	30.5 ± 0.5^a,b	29 ± 1^a,b		34.5 ± 0.5^a,b
Sodium (mmol/L)
Injured	137.1 ± 0.738^a	138.7 ± 1.063^a	144.3 ± 1.93^*	146.4 ± 1.73^b
Sham	135.5 ± 0.5	139 ± 2		137 ± 1
Glucose (mg/dL)
Injured	102.7 ± 10.32	181.1 ± 35.04	223 ± 45.44^†	153.57 ± 15.25
Sham	108 ± 22	82 ± 21		211.5 ± 42.5
Hematocrit % (PCU)
Injured	21.71 ± 1.17^a	27.57 ± 1.325^b	20.83 ± 2.12	16.86 ± 2.849^a
Sham	22.5 ± 1.5^a,b	29.5 ± 0.5^a,b		21.5 ± 2.5^a,b
Hemoglobin (g/dL)
Injured	7.371 ± 0.398^a	9.41 ± 0.436^b	7.017 ± 0.696	5.743 ± 0.971^a
Sham	7.65 ± 0.55^a,b	10.05 ± 0.15^a,b		7.35 ± 0.85^a,b
Lactate (mmol/L)
Injured	1.1 ± 0.084	4.823 ± 1.513^‡	3.027 ± 0.916	0.853 ± 0.125^§
Sham	0.7 ± 0.4	0.83 ± 0.23		1.015 ± 0.215

Data are expressed as means ± SEM. Means with different letters differ via two-way repeated measure with Tukey-Kramer's post hoc test, p < 0.05.

^{^*}

8–16 h post-injury differs from pre-injury in injured piglets via one-way analysis of variance (ANOVA).

^{^†}

8–16 h post-injury tended to be different than pre-injury in injured piglets via one-way ANOVA, p = 0.0515.

^{^‡}

4–7 h post-injury differs from pre-injury in injured piglets via one-way ANOVA.

^{^§}

Sacrifice differs from 4–7 h post-injury in injured piglets via one-way ANOVA.

SEM, standard error of the mean.