FIG. 10.

Repetitive head injuries results in modest increases of activated microglia in the corpus callosum. (A). Percent area of thresholded Iba1 staining was significantly increased in animals sustaining 20 × concussive injuries at the chronic time-point relative to 20 × shams (p = 0.0327). (B) Staining was thresholded using the Sauvola thresholding method in order to quantify Iba1 staining. The automated thresholding method identified increased microglial cell bodies in the 20 × concussive animals relative to shams. Scale bar = 200 microns. Color image is available online.