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. 2019 Feb 20;7:e6388. doi: 10.7717/peerj.6388

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©2019 Saleembhasha and Mishra

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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E2F1, FOXM1 and PVT1 genes are identified as common significantly differentially expressed coding and non-coding genes from our analysis. E2F1 up-regulates FOXM1 expression and FOXM1 up-regulates PVT1 lncRNA expression. PVT1 may play a role in regulation of mRNA splicing, stability and degradation of target genes to which it is predicted to bind such as DNAJC9, RNPS1, ATXN2L, ALAD, IRAK1, FOXM1 and SYNE1.