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. 2019 Feb 13;15:457–468. doi: 10.2147/NDT.S196665

Figure 1.

Figure 1

A Kaplan–Meier plot demonstrates time to first response among 328 participants in the VNS + TAU group and 271 participants in the TAU group.

Notes: Time to first response was defined as the time from baseline to the first visit with a reduction in MADRS score of ≥50% compared to baseline. Median time to the first response was 18.1 months (Q1=6.9, Q3=49.1) for VNS + TAU participants compared to 49.1 months (Q1=12.3, Q3= not estimable) for TAU participants.

Abbreviations: MADRS, Montgomery–Åsberg Depression Rating Scale; TAU, treatment as usual; VNS, vagus nerve stimulation.