Figure 2.

A Kaplan–Meier plot for durability of the first response that occurred within the first year.

Notes: Duration of first response was defined as the time from first response to the first visit when reduction in MADRS score was <40% compared to baseline (ie, relapse). Median time to relapse from first response in first year was 10.1 months (Q1=4.2, Q3=31.5) for VNS + TAU and 7.3 months (Q1=3.1, Q3=17.6) for TAU.

Abbreviations: MADRS, Montgomery–Åsberg Depression Rating Scale; TAU, treatment as usual; VNS, vagus nerve stimulation.