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. Author manuscript; available in PMC: 2019 Feb 23.
Published in final edited form as: Trends Genet. 2018 Dec 4;35(2):129–144. doi: 10.1016/j.tig.2018.11.001

Figure 2. G4 in Gene Regulation.

Figure 2

(A) G-quadruplexes (G4s) are enriched near transcription start sites (TSS) of multiple species. Adapted, with permission, from [28]. (B) Reported trans-acting factors that are recruited to promoter G4s. (C) Schematic showing different mechanisms by which promoter G4s might affect recruitment of regulatory trans-acting factors.