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. Author manuscript; available in PMC: 2019 Feb 23.
Published in final edited form as: Trends Genet. 2018 Dec 4;35(2):129–144. doi: 10.1016/j.tig.2018.11.001

Table 1. G4 Motifs (G3L1-7) Mapped on the hTERT Promoter and Positions of Reported Transcription Factors Have Been Marked.

Upstream distance from translational start site (bp) Length of G4 motif G3L1-7 motifs Transcription factor binding sites
102 18 GGGGAGGGGCTGGGAGGG TEIF, Sp1 GABP-α on – 124G > A mutation
18 GGGGAGGGGCTGGGAGGG
27 GGGGAGGGGCTGGGAGGGCCCGGAGGG
27 GGGGAGGGGCTGGGAGGGCCCGGAGGG
28 GGGGAGGGGCTGGGAGGGCCCGGAGGGG
28 GGGGAGGGGCTGGGAGGGCCCGGAGGGG
103 17 GGGAGGGGCTGGGAGGG
17 GGGAGGGGCTGGGAGGG
26 GGGAGGGGCTGGGAGGGCCCGGAGGG
26 GGGAGGGGCTGGGAGGGCCCGGAGGG
26 GGGAGGGGCTGGGAGGGCCCGGAGGG
27 GGGAGGGGCTGGGAGGGCCCGGAGGGG
27 GGGAGGGGCTGGGAGGGCCCGGAGGGG
27 GGGAGGGGCTGGGAGGGCCCGGAGGGG
107 22 GGGGCTGGGAGGGCCCGGAGGG
23 GGGGCTGGGAGGGCCCGGAGGGG
29 GGGGCTGGGAGGGCCCGGAGGGGGCTGGG
29 GGGGCTGGGAGGGCCCGGAGGGGGCTGGG
108 21 GGGCTGGGAGGGCCCGGAGGG
22 GGGCTGGGAGGGCCCGGAGGGG
28 GGGCTGGGAGGGCCCGGAGGGGGCTGGG
28 GGGCTGGGAGGGCCCGGAGGGGGCTGGG
113 23 GGGAGGGCCCGGAGGGGGCTGGG
23 GGGAGGGCCCGGAGGGGGCTGGG
117 24 GGGCCCGGAGGGGGCTGGGCCGGG
24 GGGCCCGGAGGGGGCTGGGCCGGG
25 GGGCCCGGAGGGGGCTGGGCCGGGG
25 GGGCCCGGAGGGGGCTGGGCCGGGG
126 23 GGGGGCTGGGCCGGGGACCCGGG
23 GGGGGCTGGGCCGGGGACCCGGG
127 22 GGGGCTGGGCCGGGGACCCGGG Sp1
22 GGGGCTGGGCCGGGGACCCGGG
128 21 GGGCTGGGCCGGGGACCCGGG
21 GGGCTGGGCCGGGGACCCGGG
25 GGGCTGGGCCGGGGACCCGGGAGGG
26 GGGCTGGGCCGGGGACCCGGGAGGGG
31 GGGCTGGGCCGGGGACCCGGGAGGGGTCGGG
133 20 GGGCCGGGGACCCGGGAGGG
20 GGGCCGGGGACCCGGGAGGG
21 GGGCCGGGGACCCGGGAGGGG
21 GGGCCGGGGACCCGGGAGGGG
26 GGGCCGGGGACCCGGGAGGGGTCGGG
26 GGGCCGGGGACCCGGGAGGGGTCGGG
138 21 GGGGACCCGGGAGGGGTCGGG
21 GGGGACCCGGGAGGGGTCGGG
26 GGGGACCCGGGAGGGGTCGGGACGGG
26 GGGGACCCGGGAGGGGTCGGGACGGG
27 GGGGACCCGGGAGGGGTCGGGACGGGG
31 GGGGACCCGGGAGGGGTCGGGACGGGGCGGG
139 20 GGGACCCGGGAGGGGTCGGG Sp1 GABP-a on -146G > A mutation
20 GGGACCCGGGAGGGGTCGGG
25 GGGACCCGGGAGGGGTCGGGACGGG
25 GGGACCCGGGAGGGGTCGGGACGGG
26 GGGACCCGGGAGGGGTCGGGACGGGG
30 GGGACCCGGGAGGGGTCGGGACGGGGGGG
146 18 GGGAGGGGTCGGGACGGG
18 GGGAGGGGTCGGGACGGG
19 GGGAGGGGTCGGGACGGGG
19 GGGAGGGGTCGGGACGGGG
23 GGGAGGGGTCGGGACGGGGCGGG
23 GGGAGGGGTCGGGACGGGGCGGG
23 GGGAGGGGTCGGGACGGGGCGGG
23 GGGAGGGGTCGGGACGGGGCGGG
23 GGGAGGGGTCGGGACGGGGCGGG
24 GGGAGGGGTCGGGACGGGGCGGGG
24 GGGAGGGGTCGGGACGGGGCGGGG
24 GGGAGGGGTCGGGACGGGGCGGGG
150 19 GGGGTCGGGACGGGGCGGG HIF1/2, Sp1, Sp3, E2F1
19 GGGGTCGGGACGGGGCGGG
20 GGGGTCGGGACGGGGCGGGG
20 GGGGTCGGGACGGGGCGGGG
151 18 GGGTCGGGACGGGGCGGG
18 GGGTCGGGACGGGGCGGG
19 GGGTCGGGACGGGGCGGGG
19 GGGTCGGGACGGGGCGGGG