Table 1.
Predicted sizes compared to experimentally determined complexes. Numbers in parenthesis after complex names indicate the reference/s of the known complex size. Mapp; Apparent mass determined based on SEC elution profile of the proteins.
| Subunit (Complex name) | Known size [kDa] (Literature) | Mapp [kDa] (This study) |
|---|---|---|
| ENL (Super Elongation Complex) (44) | 337 | 649 |
| EZH2 (PRC2) (46) | 444 | 500 |
| HDAC3 (NCOR) (45) | 501 | 649 |
| CHD4 (NuRD) (37) | 505 | 649 |
| SIN3a (SIN3a/HDAC) (37) | 398 | 649 |
| PSA1 (20S Proteasome) (42) | 700 | 500 |
| TRAP1 (19S proteasome) (42) | 900 | 649 |
| TRAP1 (19S proteasome) (42) | 301 | 228 |
| SSRP1 (FACT) (2) | 195 | 228 |
| MSH6 (MSH2/6-PCNA) (2) | 285 | 296 |