Figure 4.

Experimental dn/dc values (green), values predicted from the additive model of Zhao et al (red) and additive model values plus the π-pair correction (blue) are plotted as a function of the experimental dn/dc. Corrected predictions are shown as filled diamonds for the lowest energy structure and empty diamonds for alternate confirmations where they are available. Two filled diamonds are shown representing the two lysozyme crystal structures, while no predictions are shown for J2-crystallin, as no previously solved structures were sufficiently similar for confident structural modeling. Additional unfilled diamonds are shown for human γS-crystallin to represent alternate low energy NMR conformations. Regression lines are shown as visual guides for model comparison.