Table 2.
Multivariate predictors of chemotherapy receipt in nonmetastatic uterine LMS.
| Variable | OR | 95% CI | P |
|---|---|---|---|
| Year of diagnosis | |||
| Per year increase | 1.16 | 1.13–1.20 | <0.0001 |
|
| |||
| Age at diagnosis, y | |||
| 18–39 | Ref | ||
| 40–49 | 0.93 | 0.67–1.31 | 0.6927 |
| 50–64 | 0.93 | 0.67–1.29 | 0.6537 |
| 65+ | 0.60 | 0.38–0.94 | 0.0264 |
|
| |||
| Race | |||
| White | Ref | ||
| African American | 0.80 | 0.63–1.02 | 0.0727 |
| Other | 1.09 | 0.78–1.53 | 0.5965 |
|
| |||
| Hispanic | |||
| Yes | 1.34 | 0.94–1.91 | 0.1112 |
| No | Ref | ||
|
| |||
| Comorbidities (Charlson/Deyo score) | |||
| 0 | Ref | ||
| 1 | 0.93 | 0.73–1.18 | 0.5332 |
| 2 | 0.72 | 0.37–1.41 | 0.3381 |
|
| |||
| Insurance status | |||
| Private | Ref | ||
| Medicare | 0.59 | 0.42–0.84 | 0.0030 |
| Medicaid | 1.06 | 0.77–1.48 | 0.7062 |
| None | 0.92 | 0.64–1.30 | 0.6265 |
| Other government | 2.42 | 1.04–5.61 | 0.0400 |
|
| |||
| Education (% no high school diploma) | |||
| ≥21 | 0.68 | 0.48–0.97 | 0.0354 |
| 13–20.9 | 0.58 | 0.43–0.79 | 0.0005 |
| 7–12.9 | 0.86 | 0.68–1.09 | 0.2143 |
| <7 | Ref | ||
|
| |||
| Median household income ($) | |||
| <38,000 | 1.49 | 1.04–2.13 | 0.0282 |
| 38,000–47,999 | 1.42 | 1.05–1.92 | 0.0239 |
| 48,000–62,999 | 1.37 | 1.07–1.75 | 0.0117 |
| >63,000 | Ref | ||
|
| |||
| Location of patient | |||
| Large metropolitan | Ref | ||
| Small metropolitan | 0.92 | 0.73–1.15 | 0.4570 |
| Suburban | 1.00 | 0.73–1.39 | 0.9764 |
| Rural | 0.69 | 0.43–1.10 | 0.1146 |
|
| |||
| Hospital volume (cases per year) | |||
| 0.09 | Ref | ||
| 0.18–0.27 | 1.00 | 0.62–1.61 | 0.9964 |
| 0.36–0.55 | 1.18 | 0.74–1.87 | 0.4912 |
| 0.64–7.27 | 1.27 | 0.82–1.98 | 0.2812 |
|
| |||
| Regional lymph nodes positive | |||
| Yes | 3.83 | 1.81–8.09 | 0.0004 |
| No | Ref | ||
|
| |||
| Stage | |||
| I | 0.32 | 0.25–0.41 | <0.0001 |
| II | 0.38 | 0.26–0.56 | <0.0001 |
| III | Ref | ||
|
| |||
| Hormone therapy | |||
| Yes | 0.72 | 0.30–1.70 | 0.4473 |
| No | Ref | ||
|
| |||
| Radiation | |||
| Yes | 1.45 | 1.17–1.79 | 0.0006 |
| No | Ref | ||
|
| |||
| Oophorectomy | |||
| Yes | 0.92 | 0.72–1.19 | 0.5395 |
| No | Ref | ||