Figure 1.

(a) Schematic of the animal experimental protocol and drug administration. Eight weeks of SCU and Met treatment regulated (b) body weight, (c) blood glucose, (d) glucose tolerance, and the levels of (e) glycated hemoglobin, (f) insulin, and (g) pyruvate kinase in serum of db/db mice. Results are represented as means ± SEM (n = 8). ^## P < 0.01 and ^### P < 0.001 in a comparison with the db/m⁺ mice, ^∗ P < 0.05, ^∗∗ P < 0.01, and ^∗∗∗ P < 0.001 in a comparison with the vehicle-treated db/db mice. SCU: scutellarin; Met: metformin.