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. 2019 Feb 18;10:52. doi: 10.3389/fgene.2019.00052

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Copyright © 2019 Korkuć, Arends and Brockmann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Imputation strategies for the 1- and 2-step imputation approaches. While in the 1-step imputation the genotypes are directly imputed from 50 k to sequence level, in the 2-step imputation the genotypes are first imputed from 50 to 700 k level after which imputation is performed to sequence level. Either the 30 DSN or the “1000 bulls” reference panel were used for imputation. Genotypes that were scaled down to 50 k or 700 k level are labeled with “^∗”. Similar colors refer to genotypes of the same 50 k (gray), 700 k (blue) or sequence (orange) level.