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ADMC functional response. Human skin MC (black box) or ADMC (gray box; 106) were challenged with or without (spontaneous release) 1 μg/ml anti-FcεRI Abs or anti-NP IgE + antigen (IgE-Ag) and degranulation (A) or GM-CSF production (B) assessed in the supernatants. Error bars represent ± SD. *p < 0.05 comparing skin MC vs. ADMC release. Figure is representative of cells derived from two different donors.
