Figure 4.

Correlation between clinical risk factors and germline mutation status. The patient characteristics of gender, age, age group, smoking history, drinking history, family history of ESCC, lesion number, T stage, N stage, differentiation, TNM stage, perineural invasion, LN positivity, and growth of new vessels were compared with the germline mutation status, which comprised the HRD VUS status, MMR VUS status, SLX4 rare VUS status, TSC2 rare VUS status, CYP21A2 pathogenic mutation status, VUS group, and P group.