Fig. 7.

Hemodynamic and neural activity from animals with minocycline with NAC administration postsoft cranial window installation. (a) An experimental scheme of the mixture of minocycline with NAC administration for 3 days postsoft cranial window installation. (b) The spatial activation map of ORIS imaging for a single-whisker stimulation (4 s) in the animal with or without minocycline with NAC at 2 weeks postsoft cranial window installation. (c) A graph of $\mathrm{\Delta }R/R$ change at 2 weeks postsoft cranial window installation in mice with or without minocycline plus NAC (minoNAC: $n=6$, 2 weeks: $n=10$). (d) The peak value of $\mathrm{\Delta }R/R$ changes. (e) LFP following C2 whisker single deflection (trials =100). (f) The peak amplitude of LFP following C2 whisker single deflection (trials = 500, $p\text{value}>0.001$). (g) Immunohistochemistry of reactive astrocyte (green) and microglia (red) of an animal treated with minoNAC.