Comparison 16. Ergometrine vs Misoprostol.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Death	7	5254	Risk Ratio (IV, Random, 95% CI)	0.0 [0.0, 0.0]
2 PPH >= 1000 mL	11	5562	Risk Ratio (IV, Random, 95% CI)	1.25 [0.45, 3.48]
3 Blood transfusion	13	5308	Risk Ratio (IV, Random, 95% CI)	1.71 [0.65, 4.50]
4 Severe maternal morbidity: intensive care admissions	1	864	Risk Ratio (IV, Random, 95% CI)	0.33 [0.01, 8.16]
5 Severe maternal morbidity: shock	0	0	Risk Ratio (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6 PPH >= 500 mL	16	6459	Risk Ratio (IV, Random, 95% CI)	1.18 [0.79, 1.75]
7 Additional uterotonics	16	6565	Risk Ratio (IV, Random, 95% CI)	1.04 [0.68, 1.60]
8 Blood loss	15	6337	Mean Difference (IV, Random, 95% CI)	11.66 [‐9.85, 33.17]
9 Change in haemoglobin	8	4438	Mean Difference (IV, Random, 95% CI)	0.91 [‐0.43, 2.26]
10 Breastfeeding	0	0	Risk Ratio (IV, Random, 95% CI)	0.0 [0.0, 0.0]
11 Nausea	13	5202	Risk Ratio (IV, Random, 95% CI)	1.53 [1.15, 2.04]
12 Vomiting	14	6136	Risk Ratio (IV, Random, 95% CI)	1.22 [0.81, 1.83]
13 Headache	8	3369	Risk Ratio (IV, Random, 95% CI)	1.70 [0.70, 4.12]
14 Abdominal pain	2	233	Risk Ratio (IV, Random, 95% CI)	1.58 [0.04, 65.80]
15 Hypertension	2	300	Risk Ratio (IV, Random, 95% CI)	7.55 [0.94, 60.53]
16 Shivering	17	6860	Risk Ratio (IV, Random, 95% CI)	0.34 [0.26, 0.44]
17 Fever	14	6330	Risk Ratio (IV, Random, 95% CI)	0.24 [0.17, 0.33]
18 Diarrhoea	8	4165	Risk Ratio (IV, Random, 95% CI)	1.04 [0.46, 2.34]
19 Maternal well‐being	0		Risk Ratio (IV, Random, 95% CI)	Totals not selected
20 Maternal satisfaction	0		Risk Ratio (IV, Random, 95% CI)	Totals not selected