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. 2018 Dec 19;2018(12):CD011689. doi: 10.1002/14651858.CD011689.pub3

Comparison 17. Misoprostol vs Ergometrine plus oxytocin.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death 4 3258 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2 PPH >= 1000 mL 9 6028 Risk Ratio (IV, Random, 95% CI) 1.61 [1.08, 2.40]
3 Blood transfusion 8 6335 Risk Ratio (IV, Random, 95% CI) 1.41 [0.91, 2.21]
4 Severe maternal morbidity: intensive care admissions 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5 Severe maternal morbidity: shock 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6 PPH >= 500 mL 10 6492 Risk Ratio (IV, Random, 95% CI) 1.75 [1.35, 2.26]
7 Additional uterotonics 9 6395 Risk Ratio (IV, Random, 95% CI) 1.87 [1.49, 2.36]
8 Blood loss 8 5634 Mean Difference (IV, Random, 95% CI) 22.86 [4.50, 41.22]
9 Change in haemoglobin 9 5588 Mean Difference (IV, Random, 95% CI) 1.09 [‐0.49, 2.67]
10 Breastfeeding 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11 Nausea 4 3399 Risk Ratio (IV, Random, 95% CI) 0.71 [0.61, 0.84]
12 Vomiting 6 4983 Risk Ratio (IV, Random, 95% CI) 0.72 [0.50, 1.04]
13 Headache 3 3259 Risk Ratio (IV, Random, 95% CI) 0.91 [0.47, 1.76]
14 Abdominal pain 1 846 Risk Ratio (IV, Random, 95% CI) 0.90 [0.79, 1.02]
15 Hypertension 3 2553 Risk Ratio (IV, Random, 95% CI) 0.50 [0.18, 1.41]
16 Shivering 6 4980 Risk Ratio (IV, Random, 95% CI) 2.71 [1.95, 3.76]
17 Fever 7 5045 Risk Ratio (IV, Random, 95% CI) 5.33 [2.87, 9.88]
18 Diarrhoea 6 3659 Risk Ratio (IV, Random, 95% CI) 1.04 [0.68, 1.57]
19 Maternal well‐being 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
20 Maternal satisfaction 1   Mean Difference (IV, Random, 95% CI) Totals not selected
20.1 Woman's satisfaction using an eight item Client Satisfaction Questionnaire 1   Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]