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. 2018 Dec 19;2018(12):CD011689. doi: 10.1002/14651858.CD011689.pub3

Comparison 40. Ergometine plus oxytocin vs Oxytocin (by mode of birth).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death 2 1314 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.1 Vaginal birth 2 1314 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2 PPH >= 1000 mL 10 10990 Risk Ratio (IV, Random, 95% CI) 0.73 [0.57, 0.93]
2.1 Vaginal birth 10 10990 Risk Ratio (IV, Random, 95% CI) 0.73 [0.57, 0.93]
2.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
3 Blood transfusion 11 10985 Risk Ratio (IV, Random, 95% CI) 0.88 [0.53, 1.44]
3.1 Vaginal birth 9 10521 Risk Ratio (IV, Random, 95% CI) 1.00 [0.61, 1.64]
3.2 Caesarean 2 464 Risk Ratio (IV, Random, 95% CI) 0.39 [0.17, 0.91]
4 Severe maternal morbidity: intensive care admissions 1 991 Risk Ratio (IV, Random, 95% CI) 2.99 [0.12, 73.32]
4.1 Vaginal birth 1 991 Risk Ratio (IV, Random, 95% CI) 2.99 [0.12, 73.32]
4.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5 Severe maternal morbidity: shock 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6 PPH >= 500 mL 11 11090 Risk Ratio (IV, Random, 95% CI) 0.72 [0.57, 0.91]
6.1 Vaginal birth 11 11090 Risk Ratio (IV, Random, 95% CI) 0.72 [0.57, 0.91]
6.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
7 Additional uterotonics 10 8968 Risk Ratio (IV, Random, 95% CI) 0.79 [0.59, 1.07]
7.1 Vaginal birth 8 8504 Risk Ratio (IV, Random, 95% CI) 0.80 [0.58, 1.10]
7.2 Caesarean 2 464 Risk Ratio (IV, Random, 95% CI) 0.74 [0.22, 2.48]
8 Blood loss 10 4248 Mean Difference (IV, Random, 95% CI) ‐10.31 [‐40.32, 19.70]
8.1 Vaginal birth 7 3729 Mean Difference (IV, Random, 95% CI) ‐0.12 [‐33.85, 33.60]
8.2 Caesarean 3 519 Mean Difference (IV, Random, 95% CI) ‐49.54 [‐88.07, ‐11.01]
9 Change in haemoglobin 6 4324 Mean Difference (IV, Random, 95% CI) ‐2.23 [‐5.24, 0.77]
9.1 Vaginal birth 6 4324 Mean Difference (IV, Random, 95% CI) ‐2.23 [‐5.24, 0.77]
9.2 Caesarean 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10 Breastfeeding 1 3483 Risk Ratio (IV, Random, 95% CI) 0.99 [0.96, 1.01]
10.1 Vaginal birth 1 3483 Risk Ratio (IV, Random, 95% CI) 0.99 [0.96, 1.01]
10.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11 Nausea 7 6931 Risk Ratio (IV, Random, 95% CI) 1.72 [0.84, 3.53]
11.1 Vaginal birth 5 6467 Risk Ratio (IV, Random, 95% CI) 1.58 [0.65, 3.86]
11.2 Caesarean 2 464 Risk Ratio (IV, Random, 95% CI) 2.09 [0.53, 8.22]
12 Vomiting 9 10227 Risk Ratio (IV, Random, 95% CI) 3.05 [1.76, 5.29]
12.1 Vaginal birth 7 9763 Risk Ratio (IV, Random, 95% CI) 2.93 [1.50, 5.71]
12.2 Caesarean 2 464 Risk Ratio (IV, Random, 95% CI) 2.83 [1.12, 7.15]
13 Headache 5 5105 Risk Ratio (IV, Random, 95% CI) 1.26 [0.79, 1.99]
13.1 Vaginal birth 4 4689 Risk Ratio (IV, Random, 95% CI) 1.74 [0.67, 4.55]
13.2 Caesarean 1 416 Risk Ratio (IV, Random, 95% CI) 1.06 [0.59, 1.91]
14 Abdominal pain 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15 Hypertension 3 1362 Risk Ratio (IV, Random, 95% CI) 2.00 [0.29, 13.97]
15.1 Vaginal birth 2 1314 Risk Ratio (IV, Random, 95% CI) 4.57 [0.65, 32.04]
15.2 Caesarean 1 48 Risk Ratio (IV, Random, 95% CI) 0.25 [0.03, 2.08]
16 Shivering 2 1591 Risk Ratio (IV, Random, 95% CI) 0.96 [0.60, 1.53]
16.1 Vaginal birth 2 1591 Risk Ratio (IV, Random, 95% CI) 0.96 [0.60, 1.53]
16.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
17 Fever 2 1591 Risk Ratio (IV, Random, 95% CI) 1.08 [0.48, 2.43]
17.1 Vaginal birth 2 1591 Risk Ratio (IV, Random, 95% CI) 1.08 [0.48, 2.43]
17.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
18 Diarrhoea 3 2030 Risk Ratio (IV, Random, 95% CI) 1.26 [0.72, 2.22]
18.1 Vaginal birth 3 2030 Risk Ratio (IV, Random, 95% CI) 1.26 [0.72, 2.22]
18.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19 Maternal well‐being 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
19.1 Vaginal birth 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19.2 Caesarean 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20 Maternal satisfaction 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
20.1 Vaginal birth 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20.2 Caesarean 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]