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. 2018 Dec 19;2018(12):CD011689. doi: 10.1002/14651858.CD011689.pub3

Comparison 48. Injectable prostaglandins vs Ergometrine (by mode of birth).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death 1 100 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.1 Vaginal birth 1 100 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2 PPH >= 1000 mL 1 50 Risk Ratio (IV, Random, 95% CI) 5.0 [0.25, 99.16]
2.1 Vaginal birth 1 50 Risk Ratio (IV, Random, 95% CI) 5.0 [0.25, 99.16]
2.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
3 Blood transfusion 4 384 Risk Ratio (IV, Random, 95% CI) 1.01 [0.04, 23.58]
3.1 Vaginal birth 4 384 Risk Ratio (IV, Random, 95% CI) 1.01 [0.04, 23.58]
3.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4 Severe maternal morbidity: intensive care admissions 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5 Severe maternal morbidity: shock 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6 PPH >= 500 mL 3 399 Risk Ratio (IV, Random, 95% CI) 1.42 [0.64, 3.17]
6.1 Vaginal birth 3 399 Risk Ratio (IV, Random, 95% CI) 1.42 [0.64, 3.17]
6.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
7 Additional uterotonics 5 684 Risk Ratio (IV, Random, 95% CI) 0.78 [0.40, 1.51]
7.1 Vaginal birth 5 684 Risk Ratio (IV, Random, 95% CI) 0.78 [0.40, 1.51]
7.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
8 Blood loss 8 1195 Mean Difference (IV, Random, 95% CI) ‐16.08 [‐57.17, 25.00]
8.1 Vaginal birth 8 1195 Mean Difference (IV, Random, 95% CI) ‐16.08 [‐57.17, 25.00]
8.2 Caesarean 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
9 Change in haemoglobin 2 300 Mean Difference (IV, Random, 95% CI) ‐1.28 [‐6.58, 4.01]
9.1 Vaginal birth 2 300 Mean Difference (IV, Random, 95% CI) ‐1.28 [‐6.58, 4.01]
9.2 Caesarean 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10 Breastfeeding 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11 Nausea 5 684 Risk Ratio (IV, Random, 95% CI) 1.70 [0.98, 2.94]
11.1 Vaginal birth 5 684 Risk Ratio (IV, Random, 95% CI) 1.70 [0.98, 2.94]
11.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
12 Vomiting 5 684 Risk Ratio (IV, Random, 95% CI) 2.70 [0.97, 7.55]
12.1 Vaginal birth 5 684 Risk Ratio (IV, Random, 95% CI) 2.70 [0.97, 7.55]
12.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
13 Headache 1 80 Risk Ratio (IV, Random, 95% CI) 2.0 [0.39, 10.31]
13.1 Vaginal birth 1 80 Risk Ratio (IV, Random, 95% CI) 2.0 [0.39, 10.31]
13.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14 Abdominal pain 3 384 Risk Ratio (IV, Random, 95% CI) 1.70 [0.07, 40.44]
14.1 Vaginal birth 3 384 Risk Ratio (IV, Random, 95% CI) 1.70 [0.07, 40.44]
14.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15 Hypertension 2 315 Risk Ratio (IV, Random, 95% CI) 0.16 [0.02, 1.37]
15.1 Vaginal birth 2 315 Risk Ratio (IV, Random, 95% CI) 0.16 [0.02, 1.37]
15.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
16 Shivering 3 434 Risk Ratio (IV, Random, 95% CI) 0.38 [0.16, 0.91]
16.1 Vaginal birth 3 434 Risk Ratio (IV, Random, 95% CI) 0.38 [0.16, 0.91]
16.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
17 Fever 4 534 Risk Ratio (IV, Random, 95% CI) 4.52 [0.76, 26.80]
17.1 Vaginal birth 4 534 Risk Ratio (IV, Random, 95% CI) 4.52 [0.76, 26.80]
17.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
18 Diarrhoea 5 664 Risk Ratio (IV, Random, 95% CI) 10.09 [2.75, 37.00]
18.1 Vaginal birth 5 664 Risk Ratio (IV, Random, 95% CI) 10.09 [2.75, 37.00]
18.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19 Maternal well‐being 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
19.1 Vaginal birth 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19.2 Caesarean 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20 Maternal satisfaction 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
20.1 Vaginal birth 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20.2 Caesarean 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]