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. 2018 Dec 19;2018(12):CD011689. doi: 10.1002/14651858.CD011689.pub3

Comparison 53. Misoprostol plus oxytocin vs Carbetocin (by mode of birth).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death 1 380 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.2 Caesarean 1 380 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2 PPH >= 1000 mL 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
3 Blood transfusion 1 380 Risk Ratio (IV, Random, 95% CI) 4.00 [0.45, 35.46]
3.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
3.2 Caesarean 1 380 Risk Ratio (IV, Random, 95% CI) 4.00 [0.45, 35.46]
4 Severe maternal morbidity: intensive care admissions 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5 Severe maternal morbidity: shock 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6 PPH >= 500 mL 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
7 Additional uterotonics 1 380 Risk Ratio (IV, Random, 95% CI) 1.19 [0.74, 1.93]
7.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
7.2 Caesarean 1 380 Risk Ratio (IV, Random, 95% CI) 1.19 [0.74, 1.93]
8 Blood loss 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
8.1 Vaginal birth 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
8.2 Caesarean 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
9 Change in haemoglobin 1 380 Mean Difference (IV, Random, 95% CI) ‐1.70 [‐3.72, 0.32]
9.1 Vaginal birth 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
9.2 Caesarean 1 380 Mean Difference (IV, Random, 95% CI) ‐1.70 [‐3.72, 0.32]
10 Breastfeeding 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11 Nausea 1 380 Risk Ratio (IV, Random, 95% CI) 1.21 [0.62, 2.39]
11.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11.2 Caesarean 1 380 Risk Ratio (IV, Random, 95% CI) 1.21 [0.62, 2.39]
12 Vomiting 1 380 Risk Ratio (IV, Random, 95% CI) 1.33 [0.58, 3.09]
12.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
12.2 Caesarean 1 380 Risk Ratio (IV, Random, 95% CI) 1.33 [0.58, 3.09]
13 Headache 1 380 Risk Ratio (IV, Random, 95% CI) 2.0 [0.37, 10.79]
13.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
13.2 Caesarean 1 380 Risk Ratio (IV, Random, 95% CI) 2.0 [0.37, 10.79]
14 Abdominal pain 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15 Hypertension 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
16 Shivering 1 380 Risk Ratio (IV, Random, 95% CI) 7.83 [3.43, 17.88]
16.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
16.2 Caesarean 1 380 Risk Ratio (IV, Random, 95% CI) 7.83 [3.43, 17.88]
17 Fever 1 380 Risk Ratio (IV, Random, 95% CI) 8.5 [1.99, 36.28]
17.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
17.2 Caesarean 1 380 Risk Ratio (IV, Random, 95% CI) 8.5 [1.99, 36.28]
18 Diarrhoea 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
18.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
18.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19 Maternal well‐being 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
19.1 Vaginal birth 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19.2 Caesarean 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20 Maternal satisfaction 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
20.1 Vaginal birth 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20.2 Caesarean 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]