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. 2018 Dec 19;2018(12):CD011689. doi: 10.1002/14651858.CD011689.pub3

Comparison 56. Misoprostol plus oxytocin vs Ergometrine plus oxytocin (by mode of birth).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2 PPH >= 1000 mL 2 1605 Risk Ratio (IV, Random, 95% CI) 1.41 [0.68, 2.94]
2.1 Vaginal birth 2 1605 Risk Ratio (IV, Random, 95% CI) 1.41 [0.68, 2.94]
2.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
3 Blood transfusion 2 1605 Risk Ratio (IV, Random, 95% CI) 0.89 [0.36, 2.19]
3.1 Vaginal birth 2 1605 Risk Ratio (IV, Random, 95% CI) 0.89 [0.36, 2.19]
3.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4 Severe maternal morbidity: intensive care admissions 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5 Severe maternal morbidity: shock 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6 PPH >= 500 mL 2 1605 Risk Ratio (IV, Random, 95% CI) 1.39 [0.65, 2.99]
6.1 Vaginal birth 2 1605 Risk Ratio (IV, Random, 95% CI) 1.39 [0.65, 2.99]
6.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
7 Additional uterotonics 2 1605 Risk Ratio (IV, Random, 95% CI) 1.48 [0.82, 2.69]
7.1 Vaginal birth 2 1605 Risk Ratio (IV, Random, 95% CI) 1.48 [0.82, 2.69]
7.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
8 Blood loss 1 802 Mean Difference (IV, Random, 95% CI) ‐16.0 [‐40.24, 8.24]
8.1 Vaginal birth 1 802 Mean Difference (IV, Random, 95% CI) ‐16.0 [‐40.24, 8.24]
8.2 Caesarean 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
9 Change in haemoglobin 2 1605 Mean Difference (IV, Random, 95% CI) ‐0.50 [‐1.72, 0.72]
9.1 Vaginal birth 2 1605 Mean Difference (IV, Random, 95% CI) ‐0.50 [‐1.72, 0.72]
9.2 Caesarean 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10 Breastfeeding 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11 Nausea 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
12 Vomiting 2 1605 Risk Ratio (IV, Random, 95% CI) 1.04 [0.23, 4.77]
12.1 Vaginal birth 2 1605 Risk Ratio (IV, Random, 95% CI) 1.04 [0.23, 4.77]
12.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
13 Headache 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
13.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
13.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14 Abdominal pain 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15 Hypertension 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15.1 Vaginal birth 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
16 Shivering 2 1605 Risk Ratio (IV, Random, 95% CI) 2.95 [2.02, 4.29]
16.1 Vaginal birth 2 1605 Risk Ratio (IV, Random, 95% CI) 2.95 [2.02, 4.29]
16.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
17 Fever 2 1605 Risk Ratio (IV, Random, 95% CI) 2.89 [1.51, 5.54]
17.1 Vaginal birth 2 1605 Risk Ratio (IV, Random, 95% CI) 2.89 [1.51, 5.54]
17.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
18 Diarrhoea 2 1605 Risk Ratio (IV, Random, 95% CI) 0.81 [0.46, 1.41]
18.1 Vaginal birth 2 1605 Risk Ratio (IV, Random, 95% CI) 0.81 [0.46, 1.41]
18.2 Caesarean 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19 Maternal well‐being 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
19.1 Vaginal birth 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19.2 Caesarean 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20 Maternal satisfaction 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
20.1 Vaginal birth 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20.2 Caesarean 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]