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. 2018 Dec 19;2018(12):CD011689. doi: 10.1002/14651858.CD011689.pub3

Comparison 80. Carbetocin vs Ergometrine plus oxytocin (by healthcare setting).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death 2 320 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.1 Hospital setting 2 320 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2 PPH >= 1000 mL 4 1210 Risk Ratio (IV, Random, 95% CI) 0.34 [0.13, 0.86]
2.1 Hospital setting 4 1210 Risk Ratio (IV, Random, 95% CI) 0.34 [0.13, 0.86]
2.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
3 Blood transfusion 4 1030 Risk Ratio (IV, Random, 95% CI) 1.42 [0.42, 4.82]
3.1 Hospital setting 4 1030 Risk Ratio (IV, Random, 95% CI) 1.42 [0.42, 4.82]
3.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4 Severe maternal morbidity: intensive care admissions 2 320 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4.1 Hospital setting 2 320 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5 Severe maternal morbidity: shock 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.1 Hospital setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
5.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6 PPH >= 500 mL 4 1030 Risk Ratio (IV, Random, 95% CI) 0.96 [0.44, 2.09]
6.1 Hospital setting 4 1030 Risk Ratio (IV, Random, 95% CI) 0.96 [0.44, 2.09]
6.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
7 Additional uterotonics 6 1530 Risk Ratio (IV, Random, 95% CI) 0.54 [0.30, 1.00]
7.1 Hospital setting 6 1530 Risk Ratio (IV, Random, 95% CI) 0.54 [0.30, 1.00]
7.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
8 Blood loss 5 1330 Mean Difference (IV, Random, 95% CI) ‐44.08 [‐82.41, ‐5.75]
8.1 Hospital setting 5 1330 Mean Difference (IV, Random, 95% CI) ‐44.08 [‐82.41, ‐5.75]
8.2 Community setting 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
9 Change in haemoglobin 5 1160 Mean Difference (IV, Random, 95% CI) ‐2.57 [‐4.32, ‐0.82]
9.1 Hospital setting 5 1160 Mean Difference (IV, Random, 95% CI) ‐2.57 [‐4.32, ‐0.82]
9.2 Community setting 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10 Breastfeeding 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10.1 Hospital setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
10.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
11 Nausea 6 1530 Risk Ratio (IV, Random, 95% CI) 0.29 [0.19, 0.45]
11.1 Hospital setting 6 1530 Risk Ratio (IV, Random, 95% CI) 0.29 [0.19, 0.45]
11.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
12 Vomiting 6 1530 Risk Ratio (IV, Random, 95% CI) 0.27 [0.16, 0.46]
12.1 Hospital setting 6 1530 Risk Ratio (IV, Random, 95% CI) 0.27 [0.16, 0.46]
12.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
13 Headache 5 1330 Risk Ratio (IV, Random, 95% CI) 1.41 [0.45, 4.38]
13.1 Hospital setting 5 1330 Risk Ratio (IV, Random, 95% CI) 1.41 [0.45, 4.38]
13.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14 Abdominal pain 4 930 Risk Ratio (IV, Random, 95% CI) 0.57 [0.36, 0.91]
14.1 Hospital setting 4 930 Risk Ratio (IV, Random, 95% CI) 0.57 [0.36, 0.91]
14.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
15 Hypertension 3 660 Risk Ratio (IV, Random, 95% CI) 0.56 [0.22, 1.39]
15.1 Hospital setting 3 660 Risk Ratio (IV, Random, 95% CI) 0.56 [0.22, 1.39]
15.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
16 Shivering 5 1290 Risk Ratio (IV, Random, 95% CI) 0.45 [0.26, 0.80]
16.1 Hospital setting 5 1290 Risk Ratio (IV, Random, 95% CI) 0.45 [0.26, 0.80]
16.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
17 Fever 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
17.1 Hospital setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
17.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
18 Diarrhoea 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
18.1 Hospital setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
18.2 Community setting 0 0 Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19 Maternal well‐being 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
19.1 Hospital setting 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
19.2 Community setting 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20 Maternal satisfaction 0   Risk Ratio (IV, Random, 95% CI) Totals not selected
20.1 Hospital setting 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
20.2 Community setting 0   Risk Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]