Methods |
2‐arm active‐controlled randomised trial |
Participants |
115 women were randomised in a hospital setting in Singapore. The population comprised women of unspecified parity, a singleton pregnancy, at unspecified risk for PPH, who delivered by vaginal delivery. Exclusion criteria were not specified. |
Interventions |
125 mcg of carboprost administered IM versus 500 mcg plus 5 IU of ergometrine plus oxytocin administered IM |
Outcomes |
The study recorded the following outcomes: additional uterotonics; manual removal of placenta; diarrhoea. |
Notes |
Contact with study authors for additional information: no. Additional data from authors: no |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Low risk |
Randomised by a random number table. |
Allocation concealment (selection bias) |
Unclear risk |
Allocation concealment was not reported. |
Blinding of participants and personnel (performance bias)
All outcomes |
Unclear risk |
Blinding (of study participants and caregivers) was unclear. |
Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
Assessor blinding was not reported. |
Objective assessment of blood loss |
Low risk |
All blood and blood clots lost in the first 2 hours after delivery were collected by mopping the blood and clots with absorbent paper, and collect the paper in a plastic bag. The bags were sent to the laboratory for processing within 2 hours of completion of blood collection. |
Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
115 women were randomised in the study, but 3 were excluded because they gave birth precipitously before preparing the bed for accurate collection of blood after randomisation. |
Selective reporting (reporting bias) |
Unclear risk |
The protocol of the study was unavailable for verification. |
Intention to treat analysis |
High risk |
Those who were excluded from the study after randomisation were not included in the analysis. |
Funding source |
Unclear risk |
Source(s) of funding for the study were not reported. |