Uncu 2015.

Methods	5‐arm controlled randomised trial
Participants	248 women were randomised in a hospital setting in Turkey. The population comprised women of parity 5 or less, a singleton pregnancy, at both high and low risk for PPH, who delivered by vaginal delivery. Exclusion criteria comprised women undergoing caesarean section, or those with placenta praevia, previous PPH, APH, non‐cephalic presentation, multiple pregnancy, intrauterine death, grand multiparity (more than 5), fibroids, pre‐eclampsia or anticoagulation therapy.
Interventions	No treatment versus 400 mcg to 800 mcg of misoprostol administered orally, vaginally or rectally
Outcomes	The study recorded the following outcomes: additional uterotonics; transfusion; third stage duration (minutes); diarrhoea; shivering; abdominal pain.
Notes	Contact with study authors for additional information: yes. Additional data from authors: no
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Generated by random tables.
Allocation concealment (selection bias)	Unclear risk	Allocation concealment was not reported.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Blinding (of study participants and caregivers) was not reported.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Assessor blinding was not reported.
Objective assessment of blood loss	Unclear risk	Methods of appraising blood loss were not reported.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Data were collected completely from all randomised study participants.
Selective reporting (reporting bias)	Unclear risk	The protocol of the study was unavailable for verification.
Intention to treat analysis	Low risk	All those who were enrolled and randomly allocated to treatment were included in the analysis, in the groups to which they were randomised.
Funding source	Unclear risk	Source(s) of funding for the study were not reported.