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. 2019 Feb 21;10(2):28–43. doi: 10.4331/wjbc.v10.i2.28

Table 1.

Identities and similarities between human proteins FEZ1, FEZ2 and UNC-76 from C. elegans

UNC-76 identity (%) UNC-76 similarity (%) FEZ1 identity (%) FEZ1 similarity (%)
FEZ1 35 46 - -
FEZ2 34 45 49 56

Alignment of 376 and 385 amino acid UNC-76, 251 amino acid FEZ2, and 392 amino acid FEZ1. It is noteworthy that the N-terminal region shows to be more divergent, but yet with substantial similarity. The C-terminal region presented three particular regions with more similarity (amino acids 179-197, 251-307, and 354-381 – numbered according to the C. elegans protein)[1]. FEZ: Fasciculation and elongation zeta/zygin; UNC: Uncoordinated.