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. 2019 Feb 11;2019:9053295. doi: 10.1155/2019/9053295

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Copyright © 2019 Guoyong Yu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Paeoniflorin inhibited HGF-mediated cell migration, invasion, and actin cytoskeleton arrangement in T98G and U251. (a-d) Paeoniflorin inhibited HGF-induced cell migration. (e-h) Paeoniflorin inhibited HGF-induced cell invasion. (i, j) Paeoniflorin inhibited HGF-induced cell actin cytoskeleton arrangement. Control: no treatment; PF: 10μM paeoniflorin treatment for 24h. HGF: 20ng/ml HGF treatment for 24h; PF+HGF: 20ng/ml HGF combined with 10μM paeoniflorin incubation for 24h. All tests were performed in triplicate and presented as mean ± standard error. ∗P < 0.05, compared with control group. ^#P < 0.05, compared with HGF group.