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. 2019 Jan 23;16(3):307. doi: 10.3390/ijerph16030307

Table 1.

Characteristics of children with a diagnosis of idiopathic and isolated GHD during childhood who were retested at the transition age.

Subject Sex Age at Diagnosis (Year) MPH (SDS) Puberal Stage MRI Treatment Period (Year) Time Off-Treatment (Year) Age at Retesting FH (SDS) Δ FH-MPH (SDS) GH-Peak (ng/mL) IGF-1 (ng/mL) BMI BMI (SDS) Glucid Profile Lipid Profile
1 F 12.70 −0.38 puberal small pituitary gland 3.5 0.5 16.90 −0.51 −0.13 32.95 237 22.10 0.35 N N
2 F 11.33 −1.08 puberal slightly reduced neurohyp signal. 4 0.33 15.84 −0.81 0.27 46.75 407 23.10 0.69 N N
3 M 5.33 −1 pre-puberal small pituitary gland 9.33 0.25 15.04 −0.03 0.97 38.74 492 19.65 −0.58 N N
4 M 10.20 −0.24 pre-puberal normal 4.5 0.42 15.11 0.1 0.34 15.45 861 18.68 −0.97 N N
5 M 11.39 −0.85 pre-puberal normal 5 0.25 17.32 −0.97 −0.12 13.79 432 18.51 −1.44 N HDL↓
6 M 13.24 −0.68 puberal normal 3 0.66 17 −0.77 −0.09 43.26 371 15.73 −2.98 N N
7 M 11.34 −1.05 pre-puberal thin stalk 4.42 0.42 16.57 −2.53 −1.48 28.24 478 17.89 −1.62 N N
8 F 12.70 −1.08 puberal normal 3.42 0.58 16.70 −1.52 −0.44 35.87 586 17.32 −1.81 N N
9 M 9.90 −0.84 pre-puberal normal 5.5 0.42 14.82 0.35 1.19 24.74 390 20.21 −0.34 N N
10 M 6.85 −1.47 pre-puberal partial empty saddle 8.92 0.33 16.20 −1.68 −0.21 59.02 317 19.43 −0.86 N N
11 F 4.20 −1.89 pre-puberal normal 7.42 0.50 12.10 −1.14 0.75 25.94 437 20.59 0.22 N TG and LDL↑
12 F 9.22 −0.44 pre-puberal normal 4.5 0.50 14.20 −0.35 0.09 66.43 364 16.76 −1.79 N N
13 M 12.35 −0.85 pre-puberal small pituitary gland 3 0.66 16.21 −1.45 −0.6 40.51 349 19.78 −0.72 N N
14 M 10 −1.08 pre-puberal small pituitary gland 5.5 0.66 16.20 −0.08 1 35.30 440 19.27 −0.92 N N
15 M 13.92 −0.90 puberal slight-asymmetry of pituitary gland 2 0.33 16.41 −0.95 −0.05 42.27 443 20.22 −0.97 N N
16 F 9.97 −0.44 pre-puberal small pituitary gland 5.42 0.33 16.80 −0.29 0.15 50.49 490 25.62 1.32 N N
17 M 8.67 −0.46 pre-puberal normal 4.5 0.25 14.90 −0.33 0.13 34.40 353 22.05 0.25 N N
18 F 9.64 0.92 pre-puberal small pituitary gland 4.33 0.42 14.83 0.10 −0.82 36.30 494 17.23 −1.64 N N
19 M 14.44 −0.85 puberal partial empty saddle 2.5 0.58 17.85 −0.46 0.39 0.44 460 22.32 0.11 N N
20 F 9.79 −1.38 pre-puberal small pituitary gland 5 0.33 15.31 −2.79 −1.41 58.63 498 26.45 1.50 N N
21 M 11.64 −0.93 pre-puberal normal 5.5 0.25 17.40 −0.55 0.38 45.54 407 20.09 −0.72 N N
22 M 6.22 0.41 pre-puberal normal 8.92 0.42 15.73 −0.61 −1.02 44.99 173 17.27 −1.64 N N
23 F 11.11 −0.68 pre-puberal small pituitary gland 3 0.42 14.95 −1.38 −0.7 96.64 730 20.40 −0.22 N N
24 M 12.95 −1.71 pre-puberal normal 3.5 0.33 16.92 −0.98 0.73 35.30 379 19.10 −1.10 N N
25 F 11.71 −0.85 puberal normal 4 0.50 16.64 −1.27 −0.42 4.64 269 26.78 1.56 N TC↑
26 F 7.74 −0.96 pre-puberal normal 7.5 0.33 15.7 −0.71 0.25 55.64 286 21.37 0.13 N N
27 F 10.66 −1.12 puberal partial empty saddle 3.5 0.42 16.64 −1.13 −0.01 25.46 386 22.01 0.36 N N
28 M 5.47 −0.77 pre-puberal normal 10.2 0.33 15.94 −0.06 0.71 16.68 453 16.35 −2.30 N N
29 M 3.34 −0.86 pre-puberal thin stalk 13 0.42 15.70 −0.64 0.22 39.32 287 21.44 −0.04 N N
30 M 12 −1.51 pre-puberal normal 4.75 0.33 17.33 −0.71 0.8 46.21 444 22.23 0.09 N N
31 M 12.17 −1.63 pre-puberal normal 3.6 0.33 17.17 −1.89 −0.26 20.40 272 25.97 1.17 N N

HDL, cholesterol high-density lipoprotein; LDL, cholesterol low-density lipoprotein; N, normal; TG, triglycerides.