Table 3.

Changes in the serum concentrations of C-reactive protein (CRP), surfactant protein D (SP-D) and club cell protein 16 (CC-16) after being adjusted for age, BMI, infection, nicotine and cotinine across a 14-day work period of drill floor workers and referents. Data are also presented for the additional adjustment for time of blood sampling.

Biomarkers		Drill Floor Workers (n = 65/51) a				Referents (n = 64/55) a,b				Drill Floor Workers vs. Referents
	Bio-Marker	Esti-Mate	Lower	Upper	p	Esti-Mate	Lower	Upper	p	Esti-Mate	Lower	Upper	p
Not adjusted for time of day	CRP c	–0.12	−0.23	0.00	0.045	−0.07	−0.18	0.05	0.25	−0.05	−0.21	0.11	0.53
	SPD c	−0.02	−0.05	0.01	0.12	−0.03	−0.06	−0.01	0.017	0.01	−0.03	0.05	0.56
	CC16	−0.71	−1.06	−0.36	0.0001	−0.59	−0.93	−0.24	0.001	−0.12	−0.62	0.37	0.62
Adjusted for time of day	CRP c	−0.14	−0.27	−0.01	0.038	−0.09	−0.23	0.05	0.19	−0.04	−0.21	0.12	0.58
	SPD c	−0.01	−0.05	0.02	0.36	−0.02	−0.06	0.01	0.2	0.01	−0.03	0.05	0.64
	CC16	−0.35	−0.77	0.07	0.1	−0.12	−0.57	0.33	0.61	−0.23	−0.73	0.26	0.36

^a Number of observations before and after shift (with complete covariate information). ^b CRP had n = 64/54 and SP-D had n = 63/54. ^c Log₁₀-transformed.