Table 1.
Cross-sectional regression parameter estimates using GEE 1 for EGFR = HIV infection, serum albumin and BUN in the Bronx WIHS.
| Variable | Working Correlation Structure | |||||
|---|---|---|---|---|---|---|
| Independence | Equicorrelation 2 | |||||
| Point Estimate | 95% CI | Z-Value (p) | Point Estimate | 95% CI | Z-Value (p) | |
| HIV Infection (βHIV,CS) |
−2.04 | (−5.07, 0.98) | −1.32 (<0.19) | −3.96 | (−6.90, −1.03) | −2.65 (0.0081) |
| Albumin Per g/dL (βALB,CS) |
−6.21 | (−8.95, −3.47) | −4.44 (<0.0001) | −9.84 | (−12.01, −7.68) | −8.93 (<0.0001) |
| BUN Per mg/dL (βBUN, CS) |
−1.87 | (−2.12, −1.62) | −14.45 (<0.0001) | −1.22 | (−1.46, −0.99) | −10.30 (<0.0001) |
| Quasi-Likelihood Information Criteria (QIC) | 10,847.14 | 10,836.27 | ||||
1 Mixed models gave essentially similar point estimates; see Appendix A. 2 Interclass correlation of residuals from GEE-E was 0.45 indicating non-independence correlation was structurally correct.