Table 2.
Within- and between-subject decomposition regression parameter estimates using GEE 1 for EGFR = HIV infection, serum albumin and BUN in the Bronx WIHS.
| Variable | Working Correlation Structure | ||||||
|---|---|---|---|---|---|---|---|
| Compartment | Independence | Equicorrelation | |||||
| Point Estimate | 95% CI | Z-Value (p) | Point Estimate | 95% CI | Z-Value (p) | ||
| HIV Infection | Between-subject (βHIV, BS) |
−1.16 | (−4.21, 1.88) |
−0.75 (0.45) |
−1.57 | (−4.47, 1.33) |
−1.06 (0.29) |
| NA 2 | --- | --- | --- | NA 2 | --- | --- | |
| Albumin Per g/dL |
Between-subject (βALB, BS) |
−3.27 | (−7.88, 1.33) |
−1.39 (0.16) |
−2.71 | (−7.00, 1.57) |
−1.24 (0.21) |
| Within-subject (βALB, WS) |
−10.70 | (−12.99, −8.40) |
−9.16 (<0.0001) | −10.70 | (−12.99, −8.40) |
−9.16 (<0.0001) | |
| BUN Per mg/dL | Between-subject (βBUN, BS) |
−2.72 | (−3.10, −2.33) |
−13.89 (<0.0001) |
−2.65 | (−3.01, −2.08) |
−14.21 (<0.0001) |
| Within-subject (βBUN, WS) |
−1.11 | (−1.34, −0.88) |
−9.31 (<0.0001) | −1.11 | (−1.34, −0.88) |
−9.31 (<0.0001) | |
| Quasi-Likelihood Information Criteria (QIC) |
10,866.64 | 10,857.62 | |||||
1 Mixed models gave essentially similar point estimates. See Appendix A 2 There is no within-subject variation for HIV infection status.