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. Author manuscript; available in PMC: 2019 Mar 18.
Published in final edited form as: Ann Intern Med. 2018 Aug 21;169(6):376–384. doi: 10.7326/M17-2242

Table 2.

Factors Associated With Detectable VL or Amount of VL in Adjusted Models Among Patients Receiving ART*

Covariate Joint Longitudinal and Survival Model
Linear Mixed Model
OR (95% CI) P Value Relative VL (95% CI) P Value
Integrase strand transfer inhibitor use 0.54 (0.51–0.57) <0.001 0.71 (0.69–0.74) <0.001
Female 1.01 (0.93–1.08) 0.89 0.98 (0.92–1.05) 0.64
Age (per decade, centered at 40 y) 0.76 (0.74–0.78) <0.001 0.83 (0.81–0.85) <0.001
Race/ethnicity (reference is white race)
 Black 1.68 (1.57–1.80) <0.001 1.60 (1.51–1.70) <0.001
 Hispanic 0.81 (0.74–0.90) <0.001 0.89 (0.82–0.96) 0.003
 Other 0.83 (0.73–0.96) 0.009 0.90 (0.80–1.00) 0.053
Calendar time (year of cohort entry, centered around 2010) 0.83 (0.83–0.84) <0.001 0.84 (0.83–0.84) <0.001
Years of follow-up 0.79 (0.79–0.80) <0.001 0.74 (0.74–0.75) <0.001

ART = antiretroviral therapy; OR = odds ratio; VL = viral load.

*

Also adjusted for site.

Outcome is detectable VL (>400 copies/mL). The survival model component is included in Appendix Table 7 (available at Annals.org).

Outcome is VL in log10 copies/mL.