Table V.
Controls | GC patients | |||||
---|---|---|---|---|---|---|
Cytokines | No (n=93) | Yes (n=4) | No (n=119) | Yes (n=21) | OR (95% CI)-GC patients (no fried foods) vs. baseline | OR (95% CI)-GC patients (ate fried foods) vs. baseline |
GM-CSF | 0.079 (0.039,0.159) | 0.051 (0.031,0.094) | 0.131 (0.067,0.187) | 0.145 (0.068,0.237) | 1.026 (0.802,1.312) | 0.801 (0.289,2.218) |
IL-1α | 0.293 (0.000,1.070) | 0.033 (0.000,9.576) | 0.041 (0.000,0.767) | 0.221 (0.000,1.115) | 0.955 (0.899,1.014) | 0.969 (0.870,1.079) |
IL-5 | 0.393 (0.110,0.640) | 0.277 (0.105,0.458) | 0.183 (0.000,0.694) | 0.131 (0.000,0.558) | 0.960 (0.699,1.317) | 0.405 (0.112,1.459) |
IL-7 | 15.100 (10.472,18.683) | 14.724 (4.075,16.863) | 11.298 (8.356,16.641) | 15.215 (10.350,20.100) | 0.945 (0.907,0.986) | 1.016 (0.950,1.086) |
IL-12/IL-23P40 | 123.266 (86.950,159.172) | 111.621 (83.974,187.829) | 156.947 (117.513,215.526) | 150.972 (121.954,258.938) | 1.007 (1.003,1.011) | 1.009 (1.003,1.015) |
IL-15 | 2.422 (1.997,2.776) | 2.299 (1.989,2.782) | 2.558 (2.167,2.948) | 2.746 (2.241,3.109) | 1.490 (0.989,2.246) | 3.073 (1.267,7.452) |
IL-16 | 200.260 (159.212,274.765) | 125.712 (86.919,427.252) | 200.262 (127.623,294.064) | 167.127 (123.668,235.033) | 1.000 (0.999,1.002) | 0.999 (0.995,1.003) |
IL-17α | 1.951 (1.362,3.008) | 1.314 (0.808,2.067) | 3.087 (2.114,4.885) | 3.501 (2.151,5.415) | 1.060 (0.981,1.146) | 1.013 (0.958,1.072) |
TNF-β | 0.230 (0.164,0.284) | 0.297 (0.178,0.574) | 0.182 (0.140,0.215) | 0.199 (0.130,0.305) | 0.584 (0.139,2.447) | 2.008 (0.057,71.297) |
VEGF | 158.303 (105.351,237.850) | 55.391 (34.283,100.227) | 113.020 (74.817,191.002) | 162.688 (102.772,215.657) | 0.998 (0.996,1.001) | 1.000 (0.996,1.005) |
IFN-γ | 5.445 (3.858,8.424) | 4.334 (3.934,5.553) | 7.297 (5.056,11.278) | 7.155 (4.997,9.383) | 1.014 (0.988,1.040) | 1.015 (0.990,1.041) |
IL-1β | 0.000 (0.000,0.252) | 0.057 (0.000,0.387) | 0.199 (0.000,0.890) | 0.293 (0.000,0.949) | 1.015 (0.980,1.050) | 0.966 (0.849,1.098) |
IL-2 | 0.172 (0.081,0.303) | 0.367 (0.124,0.860) | 0.286 (0.180,0.478) | 0.396 (0.211,0.477) | 1.660 (0.891,3.093) | 1.353 (0.546,3.355) |
IL-4 | 0.010 (0.002,0.020) | 0.003 (0.001,0.003) | 0.007 (0.000,0.020) | 0.000 (0.000,0.008) | 94.001 (0.013,680794.795) | 0.000 (0.000,198276.564) |
IL-6 | 0.842 (0.497,1.633) | 0.559 (0.379,0.674) | 1.752 (0.877,3.704) | 1.633 (0.950,3.319) | 0.996 (0.987,1.005) | 0.988 (0.957,1.020) |
IL-8 | 42.029 (23.615,114.816) | 53.564 (18.520,104.958) | 105.997 (45.316,262.843) | 106.218 (51.928,244.294) | 1.000 (1.000,1.001) | 1.000 (0.999,1.001) |
IL-10 | 0.378 (0.258,0.509) | 0.390 (0.301,0.519) | 0.567 (0.360,0.827) | 0.546 (0.375,0.932) | 2.335 (1.182,4.614) | 1.451 (0.725,2.902) |
IL-12p70 | 0.107 (0.038,0.168) | 0.150 (0.032,0.200) | 0.199 (0.094,0.356) | 0.189 (0.080,0.441) | 1.328 (0.861,2.049) | 1.200 (0.523,2.753) |
IL-13 | 0.684 (0.163,1.660) | 0.824 (0.148,1.651) | 0.863 (0.352,1.330) | 0.943 (0.359,1.884) | 1.037 (0.884,1.217) | 1.053 (0.753,1.472) |
TNF-α | 3.147 (2.520,3.977) | 2.327 (1.727,2.480) | 4.307 (3.343,5.807) | 4.073 (3.110,5.400) | 1.014 (0.977,1.051) | 0.988 (0.916,1.064) |
The serum concentration of inflammatory cytokines is presented as the Median (P25, P75) pg/ml. All ORs were adjusted for age and sex. GC, gastric cancer; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-, interleukin; TNF-α, tumor necrosis factor-α; VEGF, vascular endothelial growth factor; IFN-γ, interferon-γ.