Table VI.
Controls | GC patients | |||||
---|---|---|---|---|---|---|
Cytokines | No (n=81) | Yes (n=16) | No (n=71) | Yes (n=69) | OR (95% CI)-GC patients (no salty foods) vs. baseline | OR (95% CI)-GC patients (ate salty foods) vs. baseline |
GM-CSF | 0.077 (0.037,0.139) | 0.120 (0.060,0.283) | 0.124 (0.062,0.182) | 0.145 (0.079,0.197) | 0.773 (0.319,1.875) | 1.155 (0.817,1.633) |
IL-1α | 0.280 (0.000,1.070) | 0.282 (0.011,1.716) | 0.000 (0.000,0.477) | 0.182 (0.000,1.127) | 0.913 (0.826,1.010) | 0.973 (0.916,1.034) |
IL-5 | 0.395 (0.123,0.671) | 0.209 (0.102,0.557) | 0.135 (0.000,0.722) | 0.195 (0.000,0.662) | 0.725 (0.407,1.292) | 0.950 (0.677,1.333) |
IL-7 | 15.290 (10.472,19.130) | 14.412 (10.244,16.363) | 13.589 (9.428,18.147) | 11.686 (8.325,15.578) | 0.969 (0.925,1.014) | 0.936 (0.888,0.987) |
IL-12/IL-23P40 | 120.444 (87.515,154.592) | 136.598 (74.028,213.588) | 156.551 (121.388,215.526) | 156.947 (117.639,230.163) | 1.009 (1.003,1.015) | 1.010 (1.004,1.015) |
IL-15 | 2.364 (1.966,2.744) | 2.526 (2.035,2.862) | 2.570 (2.155,3.023) | 2.498 (2.182,2.948) | 1.720 (1.010,2.929) | 1.867 (1.092,3.192) |
IL-16 | 199.390 (154.254,274.680) | 203.437 (145.699,289.807) | 205.724 (136.373,277.027) | 167.127 (123.739,297.283) | 1.000 (0.997,1.002) | 1.001 (0.999,1.002) |
IL-17α | 1.870 (1.294,2.957) | 2.095 (1.387,3.010) | 3.041 (1.868,4.917) | 3.374 (2.195,4.843) | 1.303 (1.089,1.560) | 1.549 (1.241,1.934) |
TNF-β | 0.235 (0.170,0.301) | 0.208 (0.145,0.279) | 0.185 (0.144,0.221) | 0.182 (0.135,0.226) | 0.792 (0.218,2.876) | 0.047 (0.002,1.288) |
VEGF | 151.324 (100.977,213.595) | 186.932 (97.193,294.212) | 141.869 (84.962,213.795) | 104.869 (70.673,177.206) | 1.000 (0.997,1.003) | 0.999 (0.996,1.002) |
IFN-γ | 5.339 (3.746,8.121) | 5.974 (4.642,10.490) | 7.820 (5.412,13.451) | 6.684 (5.011,10.059) | 1.022 (0.992,1.052) | 1.012 (0.986,1.040) |
IL-1β | 0.007 (0.000,0.275) | 0.000 (0.000,0.176) | 0.161 (0.000,1.109) | 0.288 (0.000,0.778) | 1.005 (0.948,1.066) | 1.028 (0.985,1.073) |
IL-2 | 0.185 (0.082,0.358) | 0.163 (0.067,0.220) | 0.271 (0.178,0.440) | 0.328 (0.192,0.488) | 1.342 (0.690,2.611) | 1.443 (0.782,2.660) |
IL-4 | 0.009 (0.002,0.020) | 0.011 (0.003,0.015) | 0.005 (0.000,0.019) | 0.007 (0.000,0.020) | 0.704 (0.000,125024.507) | 88.073 (0.014,562707.537) |
IL-6 | 0.741 (0.491,1.607) | 0.972 (0.642,1.575) | 1.534 (0.836,3.275) | 1.903 (0.963,4.125) | 0.990 (0.972,1.008) | 0.999 (0.989,1.008) |
IL-8 | 44.512 (23.615,113.059) | 36.606 (23.121,109.522) | 93.006 (39.910,219.404) | 121.471 (60.517,266.342) | 1.000 (1.000,1.001) | 1.000 (1.000,1.001) |
IL-10 | 0.378 (0.267,0.531) | 0.391 (0.232,0.484) | 0.588 (0.412,0.827) | 0.520 (0.344,0.946) | 5.325 (1.781,15.917) | 3.863 (1.486,10.039) |
IL-12p70 | 0.107 (0.040,0.168) | 0.111 (0.027,0.234) | 0.163 (0.073,0.350) | 0.212 (0.126,0.414) | 1.681 (0.806,3.504) | 1.656 (0.809,3.392) |
IL-13 | 0.638 (0.163,1.695) | 0.726 (0.095,1.377) | 0.897 (0.197,1.261) | 0.863 (0.494,1.584) | 0.974 (0.769,1.234) | 1.101 (0.915,1.324) |
TNF-α | 3.119 (2.487,3.961) | 3.324 (2.460,3.962) | 4.388 (3.343,5.807) | 4.272 (3.253,5.618) | 1.019 (0.967,1.073) | 1.018 (0.978,1.059) |
The serum concentration of inflammatory cytokines is presented as the Median (P25, P75) pg/ml. All ORs were adjusted for age and sex. GC, gastric cancer; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-, interleukin; TNF-α, tumor necrosis factor-α; VEGF, vascular endothelial growth factor; IFN-γ, interferon-γ.