Table VII.
Controls | GC patients | |||||
---|---|---|---|---|---|---|
Cytokines | No (n=79) | Yes (n=18) | No (n=76) | Yes (n=64) | OR (95% CI)-GC patients (not fast eaters) vs. baseline | OR (95% CI)-GC patients who ate quickly vs. baseline |
GM-CSF | 0.075 (0.036,0.135) | 0.164 (0.065,0.454) | 0.142 (0.078,0.201) | 0.115 (0.049,0.189) | 1.774 (0.336,9.374) | 3.335 (0.496,22.412) |
IL-1α | 0.144 (0.000,0.758) | 1.292 (0.153,4.888) | 0.068 (0.000,0.898) | 0.023 (0.000,0.727) | 0.975 (0.911,1.044) | 0.968 (0.899,1.042) |
IL-5 | 0.350 (0.107,0.638) | 0.368 (0.160,0.648) | 0.322 (0.000,0.783) | 0.000 (0.000,0.540) | 0.788 (0.494,1.257) | 1.015 (0.685,1.505) |
IL-7 | 15.153 (10.468,18.481) | 13.002 (10.735,16.539) | 13.060 (9.350,17.407) | 11.074 (7.863,16.971) | 0.937 (0.889,0.988) | 0.970 (0.927,1.015) |
IL-12/IL-23P40 | 121.949 (83.309,155.971) | 129.493 (96.381,188.766) | 167.081 (123.557,225.102) | 140.751 (117.308,197.323) | 1.006 (1.001,1.011) | 1.010 (1.005,1.016) |
IL-15 | 2.440 (2.080,2.841) | 2.337 (1.808,2.562) | 2.621 (2.231,3.044) | 2.494 (2.083,2.943) | 1.156 (0.679,1.969) | 1.904 (1.139,3.184) |
IL-16 | 199.390 (156.719,276.649) | 199.774 (114.951,224.620) | 207.139 (141.633,297.251) | 173.833 (116.112,256.174) | 0.999 (0.997,1.002) | 1.001 (0.999,1.002) |
IL-17α | 1.878 (1.357,3.015) | 2.011 (1.163,2.933) | 3.549 (2.124,5.628) | 2.998 (2.061,4.247) | 1.427 (1.127,1.807) | 1.500 (1.221,1.843) |
TNF-β | 0.232 (0.157,0.283) | 0.216 (0.181,0.319) | 0.189 (0.145,0.226) | 0.174 (0.127,0.212) | 0.017 (0.000,0.637) | 1.038 (0.298,3.616) |
VEGF | 140.726 (98.595,224.113) | 169.453 (103.350,306.575) | 125.210 (84.439,190.594) | 105.902 (74.628,207.426) | 0.997 (0.993,1.000) | 1.000 (0.998,1.003) |
IFN-γ | 5.339 (3.768,8.150) | 6.089 (4.563,9.682) | 7.696 (5.498,11.454) | 6.764 (4.477,11.131) | 1.009 (0.985,1.033) | 1.015 (0.988,1.042) |
IL-1β | 0.000 (0.000,0.236) | 0.157 (0.000,4.238) | 0.268 (0.000,1.112) | 0.073 (0.000,0.728) | 1.220 (0.945,1.574) | 1.452 (1.032,2.043) |
IL-2 | 0.172 (0.071,0.308) | 0.203 (0.093,0.663) | 0.300 (0.181,0.477) | 0.296 (0.181,0.476) | 3.118 (1.080,8.995) | 3.240 (1.066,9.854) |
IL-4 | 0.008 (0.002,0.015) | 0.020 (0.009,0.049) | 0.006 (0.000,0.018) | 0.007 (0.000,0.019) | 142.336 (0.850,238.255) | 69.780 (0.007,676.801) |
IL-6 | 0.715 (0.492,1.286) | 1.326 (0.592,15.151) | 1.845 (0.920,3.765) | 1.652 (0.908,3.209) | 1.005 (0.991,1.020) | 0.999 (0.978,1.021) |
IL-8 | 37.914 (23.377,85.643) | 91.583 (25.674,807.899) | 109.602 (56.306,259.981) | 95.472 (35.658,264.045) | 1.001 (1.000,1.002) | 1.002 (1.000,1.003) |
IL-10 | 0.378 (0.247,0.499) | 0.407 (0.326,0.704) | 0.588 (0.410,0.908) | 0.540 (0.333,0.827) | 6.886 (1.888,25.109) | 14.381 (3.631,56.955) |
IL-12p70 | 0.092 (0.030,0.148) | 0.211 (0.127,0.872) | 0.207 (0.106,0.371) | 0.168 (0.068,0.378) | 2.125 (0.816,5.533) | 3.363 (0.930,12.164) |
IL-13 | 0.638 (0.163,1.462) | 1.310 (0.295,3.018) | 0.966 (0.604,1.280) | 0.702 (0.099,1.549) | 1.156 (0.923,1.448) | 1.202 (0.880,1.641) |
TNF-α | 3.109 (2.476,3.861) | 3.424 (2.851,21.007) | 4.597 (3.423,5.901) | 4.064 (3.306,5.586) | 1.064 (0.975,1.160) | 1.113 (1.004,1.233) |
The serum concentration of inflammatory cytokines is presented as the Median (P25, P75) pg/ml. All ORs were adjusted for age and sex. GC, gastric cancer; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-, interleukin; TNF-α, tumor necrosis factor-α; VEGF, vascular endothelial growth factor; IFN-γ, interferon-γ.