Table VIII.
Association between eating fresh fruits and the serum levels of inflammatory cytokines.
| Controls | GC patients | |||||
|---|---|---|---|---|---|---|
| Cytokines | Yes (n=65) | No (n=32) | Yes (n=55) | No (n=85) | OR (95% CI)-GC patients who ate fresh fruits vs. baseline | OR (95% CI)-GC patients (no fresh fruits) vs. baseline |
| GM-CSF | 0.079 (0.045,0.165) | 0.070 (0.032,0.125) | 0.144 (0.080,0.197) | 0.114 (0.063,0.186) | 0.535 (0.167,1.712) | 1.026 (0.794,1.325) |
| IL-1α | 0.092 (0.000,1.070) | 0.443 (0.095,2.430) | 0.006 (0.000,0.870) | 0.062 (0.000,0.802) | 0.913 (0.803,1.039) | 0.979 (0.920,1.041) |
| IL-5 | 0.342 (0.104,0.640) | 0.434 (0.163,0.628) | 0.183 (0.000,0.922) | 0.136 (0.000,0.633) | 1.033 (0.706,1.510) | 0.741 (0.463,1.185) |
| IL-7 | 15.153 (10.736,19.489) | 14.577 (10.378,17.662) | 13.514 (9.794,17.663) | 11.225 (7.881,16.834) | 0.962 (0.910,1.017) | 0.950 (0.905,0.997) |
| IL-12/IL-23P40 | 126.339 (100.216,163.800) | 98.209 (69.835,146.814) | 168.958 (133.220,233.948) | 146.196 (112.486,207.672) | 1.009 (1.003,1.014) | 1.005 (1.000,1.010) |
| IL-15 | 2.422 (1.901,2.835) | 2.404 (2.122,2.673) | 2.649 (2.280,3.049) | 2.471 (2.119,2.956) | 2.051 (1.118,3.760) | 1.314 (0.837,2.062) |
| IL-16 | 200.260 (160.257,278.238) | 188.246 (129.019,238.772) | 203.345 (133.748,294.064) | 190.635 (126.537,272.428) | 1.000 (0.998,1.002) | 1.000 (0.998,1.002) |
| IL-17α | 2.107 (1.454,3.124) | 1.601 (0.983,2.450) | 3.352 (2.154,6.031) | 3.087 (2.058,4.408) | 1.035 (0.971,1.104) | 1.007 (0.956,1.061) |
| TNF-β | 0.234 (0.171,0.306) | 0.230 (0.132,0.273) | 0.193 (0.146,0.237) | 0.177 (0.131,0.215) | 1.147 (0.330,3.993) | 0.001 (0.000,0.060) |
| VEGF | 165.703 (107.712,227.465) | 134.992 (76.510,237.658) | 114.251 (70.978,169.523) | 118.829 (82.282,218.760) | 0.995 (0.990,0.999) | 1.000 (0.997,1.002) |
| IFN-γ | 5.532 (3.925,8.926) | 4.942 (3.827,6.739) | 6.889 (4.974,13.690) | 7.247 (5.345,10.969) | 1.028 (0.994,1.063) | 1.018 (0.984,1.052) |
| IL-1β | 0.007 (0.000,0.252) | 0.000 (0.000,0.240) | 0.278 (0.000,0.749) | 0.090 (0.000,1.080) | 0.983 (0.928,1.040) | 1.007 (0.975,1.041) |
| IL-2 | 0.172 (0.073,0.325) | 0.192 (0.093,0.353) | 0.303 (0.205,0.433) | 0.296 (0.173,0.491) | 1.182 (0.413,3.382) | 2.155 (0.953,4.873) |
| IL-4 | 0.010 (0.002,0.020) | 0.007 (0.002,0.014) | 0.006 (0.000,0.019) | 0.006 (0.000,0.018) | 2.169 (0.000,563.389) | 3.319 (0.001,124.466) |
| IL-6 | 1.031 (0.507,1.733) | 0.656 (0.491,1.072) | 1.672 (0.796,3.180) | 1.830 (0.946,3.912) | 0.986 (0.963,1.010) | 0.996 (0.986,1.007) |
| IL-8 | 42.572 (24.816,125.972) | 35.791 (21.201,108.237) | 96.510 (46.149,208.660) | 109.121 (47.782,278.270) | 1.000 (0.999,1.001) | 1.000 (1.000,1.001) |
| IL-10 | 0.382 (0.258,0.531) | 0.378 (0.265,0.485) | 0.546 (0.388,0.770) | 0.614 (0.353,0.922) | 1.786 (0.693,4.605) | 2.471 (1.068,5.714) |
| IL-12p70 | 0.114 (0.051,0.182) | 0.095 (0.007,0.157) | 0.209 (0.110,0.369) | 0.179 (0.075,0.380) | 1.280 (0.755,2.173) | 1.434 (0.787,2.614) |
| IL-13 | 0.684 (0.264,1.743) | 0.661 (0.000,1.458) | 0.977 (0.478,1.330) | 0.863 (0.168,1.415) | 0.959 (0.736,1.248) | 1.013 (0.853,1.202) |
| TNF-α | 3.144 (2.477,3.977) | 3.094 (2.500,3.935) | 4.086 (3.324,5.697) | 4.394 (3.344,5.793) | 0.982 (0.927,1.041) | 1.007 (0.970,1.046) |
The serum concentration of inflammatory cytokines is presented as the Median (P25, P75) pg/ml. All ORs were adjusted for age and sex. GC, gastric cancer; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-, interleukin; TNF-α, tumor necrosis factor-α; VEGF, vascular endothelial growth factor; IFN-γ, interferon-γ.