Comparison of histopathologic characteristics between irregular rim-like enhancement (IRE)-HCCs and non-IRE-HCCs based on the combined results of two reviewers' classifications. Comparison of the proportion of macrotrabecular pattern (a), microvascular density (b), sinusoid-like microvascular pattern (c), tumor necrosis (d), and fibrous stroma (e) between IRE-HCCs, HCCs with intermediate enhancement pattern, and non-IRE-HCCs. f–h The correlation between microvascular density, the proportion of capillary-like microvascular pattern, sinusoid-like microvascular pattern, macrotrabecular pattern, and tumor necrosis. Comparison of expression of keratin 19 (K19) (i), epithelial cell adhesion molecule (EpCAM) (j), and carbonic anhydrase IX (CAIX) (k) as assessed by immunohistochemistry in HCCs with intermediate enhancement pattern.