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Numerical output for the experiment when GTP is replaced by GTPγS. The parameter values are the same as in Figure 19 with h5 = 0 to simulate the fact that αi-GTPγS is also nonhydrolyzable. The stimulus is 10−8 M for t ∈ (0, 5) and 10−7 M for t ∈ (5, 10). (a) Dimensionless concentrations of HRs (solid line) and cAMPi/10 (dashed line). (b) Dimensional secretion rate of cAMPi (molecules per cell per minute). (b) should be compared with (b) in Figure 19.
