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The response of the model to a prolonged stimulus of 10−6 M extracellular cAMP. The stimulus is [H] = 1.0 μM from t = 0 to t = 8 min. (a) The dimensionless concentrations of HRs (solid line) and cAMPi/10 (dashed line). (b) The dimensional secretion rate of cAMPi in molecules per cell per minute. Compare with Figure 7 for experimental data.
