Skip to main content
. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Health Phys. 2019 Apr;116(4):546–557. doi: 10.1097/HP.0000000000000950

Figure 3. Long-term engraftment potential of primitive hematopoietic populations in TBI-Veh and NI mice in competitive transplantation assays.

Figure 3.

TBI-Veh and NI mice were assessed at various times up to 27 mo. post-irradiation for long-term engraftment potential of primitive KSLCD150+ cells. Lethally irradiated congenic murine recipients were transplanted with 150 KSLCD150+ donor cells, along with 1–2×105 LDBM competitor cells of congenic origin. Peripheral blood samples from tail-snips were obtained from transplanted recipients and analyzed by flow cytometry to determine donor chimerism using antibodies against CD45.1 and CD45.2. Lines represent mean ± SEM; * p < 0.01 comparing TBI-Veh to non-irradiated age-matched controls. The number of donor and recipient mice at each time point are given below the figure.