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. Author manuscript; available in PMC: 2019 Feb 25.
Published in final edited form as: J Alzheimers Dis. 2018;66(3):947–970. doi: 10.3233/JAD-180164

Table 3b.

Change over time in telomere length, telomerase activity and plasma Aβ levels in older adults with subjective cognitive decline randomized to a 12-week Kirtan Kriya meditation (KK) or a 12-week music listening (ML) program

Outcome Measures Change from Baseline (KK)
Change from Baseline (ML)
3 months
Mean (SE)
p* ES 3 months
Mean (SE)
p* ES p
Telomere length (absolute mean, kb) 0.29 (2.23) 0.38 0.27 –2.25 (2.50) 0.20 0.10 0.32
Telomerase activity (TSR8 copies) 1048.88 (2733.45) 0.71 0.10 1218.34 (1448.81) 0.12 0.28 0.87
Plasma Aβ (pg/ml)
  Aβ38 3.33 (13.32) 0.81 0.01 1.26 (9.08) 0.57 0.01 0.64
  Aβ40 2.04 (5.23) 0.71 0.09 –14.13 (7.16) 0.06 0.27 0.04
  Aβ42 0.42 (1.74) 0.81 0.01 0.41 (0.41) 0.63 0.04 0.77
  Ratio Aβ42/Aβ40 0.001 (0.01) 0.33 0.02 0.004 (0.001) 0.01 0.14 0.098
*

Repeated measures ANOVA

Between group difference at 3 months (P’s and effect sizes calculated on log-transformed values, adjusted for age and baseline values). ES, effect size; SE, standard error.