Table 1.
Demographic, Clinical, and Radiochemical Information of the 46 Study Participants
| Smoker | Nonsmoker | p Value | |
|---|---|---|---|
| Number of Subjects | 18 | 28 | |
| Age, Years | 35 ± 10 | 32 ± 10 | .297 |
| Body Mass Index, kg/m2 | 27 ± 6 | 27 ± 4 | .692 |
| Racea | 6 C, 7 AA, 2 A | 15 C, 10 AA, 3 A | .757 |
| Amount of Tobacco Use, Cigarettes/Dayb | 12 ± 7 | NA | NA |
| Duration of Tobacco Use, Yearsc | 15 ± 9 | NA | NA |
| Age at Onset of Tobacco Use, Yearsc | 20 ± 8 | NA | NA |
| Fagerström Test for Nicotine Dependence Scoreb | 4 ± 2 | NA | NA |
| Injected Activity of [18F]FMPEP-d2, MBq | 182 ± 11 | 182 ± 8 | .940 |
| Injected Amount of [18F]FMPEP-d2, nmol | 2.7 ± 1.1 | 1.6 ± 0.5 | .001 |
| Fraction of Free [18F]FMPEP-d2 in Plasma, % | 0.48 ± 0.1 | 0.40 ± 0.2 | .154 |
Values are n or mean ± SD.
A, Asian; AA, African American; C, Caucasian; NA, not applicable.
a
Data missing from 3 subjects.
b
Data missing from 2 subjects.
c
Data missing from 4 subjects.