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. Author manuscript; available in PMC: 2019 Feb 25.
Published in final edited form as: J Med Chem. 2018 Mar 20;61(7):2737–2752. doi: 10.1021/acs.jmedchem.7b01514

Figure 7.

Figure 7.

Induction of apoptosis in MDA-MB-231 breast cancer cells by 44. (A) Flow-cytometry analysis of apoptotic MDA-MB-231 breast cancer cells induced by 44 at different concentrations. (B) Apoptotic ratio of different concentrations of 44 in MDA-MB-231 breast cancer cells. The values are means ± SD of at least three independent experiments. A single asterisk represents p < 0.05, two asterisks represent p < 0.01, and three asterisks represent p < 0.001 to 0 μM group (DMSO, vehicle control). (C) Western-blot analysis of biomarkers for apoptosis induced by 44 in MDA-MB-231 breast cancer cells at different concentrations (48 h).