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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Pharmacol Res. 2018 Nov 10;140:21–32. doi: 10.1016/j.phrs.2018.11.013

Fig. 1. Glucose tolerance of pregnant dams is slightly impaired by metformin treatment.

Fig. 1.

A. Glucose tolerance test results from mid-gestation (ED 12-16) dams after 16 h (overnight) fast at baseline and 15 −120 min after injection of glucose (1 g/kg) did not reveal any differences between control (black circles, N = 5) or metformin (open boxes, N = 7) treatments at any specific time points. B. Comparison of area under curve (AUC) values from the glucose tolerance test revealed a slight but significant increase in metformin-treated dams relative to vehicle controls (* p < 0.05). Data are presented as means ± SEM.