Table 1.
Participant demographics
| Participants | HBV Monoinfection N = 30 | HBV/HIV Coinfection N = 15 | Healthy Controls N = 20 | P value HBV&HBV/HIV | P value HBV&HC | P value HC& HBV/HIV |
|---|---|---|---|---|---|---|
| Age (Avg ± STD) Median (IQR) |
41.1 ± 14.95 35 (27.5) |
45.1 ± 7.9 45 (40) |
26.9 ± 6.1 26 (22) |
NS | < 0.001 | < 0.001 |
| Race | ||||||
| Black | 8 | 3 | 5 | |||
| White | 9 | 11 | 11 | |||
| Asian | 12 | 0 | 4 | |||
| Hispanic | 0 | 1 | 0 | |||
| ALT U/L (Avg ± STD) Median (IQR) |
47.75 ± 47.8 40 (23.25) |
153.7 ± 132.8 115.5 (59.25) |
ND | < 0.01 | < 0.01 | < 0.01 |
| AST U/L (Avg ± STD) Median (IQR) |
31.1 ± 26.8 29.5 (21) |
108.1 ± 73.4 109.5 (41) |
ND | < 0.01 | < 0.01 | < 0.01 |
| HBV log copies/mL (Avg ± STD) Median (IQR) |
4.98 ± 2.3 4.65 (3.46) |
6.4 ± 1.2 6.47 (5.3) |
ND | NS | ND | ND |
| *% of patient with Cirrhosis | 25% | 25% | 0 | NS | ND | ND |
| HIV log copies/mL (Avg ± STD) Median (IQR) |
NA | 6501 ± 9369 4440 (2.7) |
ND | ND | ND | ND |
| % of patients with detectable HIV | NA | 91% | ND | ND | ND | ND |
| CD4 count (Avg ± STD) Median, IQR |
ND | 536 ± 285 520 (236) |
ND | ND | ND | ND |
ND = not done, NS = Not significant
* AST/ALT ratio (AAR) was used as marker of cirrhosis (> 1) for the enrolled subjects