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Template design and characterization. (A) Design of the template in AutoCAD. (B) Template produced in a 500 μm thick polyimide sheet. (C, D) Light microscopy of each topography in the polyimide sheet, showing diameter and spacing of holes. Area of each sheet in (C) is 1 × 1 cm. (E) SEM images of PLGA membrane placed on top of the topographies after applying 20 kPa vacuum pressure for 30 min. Scale bars in (E) are 1 mm. SEM, scanning electron microscopy.
