Table 3.

Resistance rate of 299 ESBL-producing Klebsiella pneumoniae strains to antimicrobial agents (%)

Antimicrobial agent	2013 (n=63)	2014 (n=49)	2015 (n=64)	2016 (n=55)	2017 (n=68)	2013–2017 (n=299)
Ceftazidime	50.8	55.1	59.7	65	74	61
Ceftriaxone	96.8	95.9	100	98.2	98.5	98
Cefepime	46	48.1	56.2	60	64.7	53.1
Cefoxitin	15.7	16.8	21	18.9	19.7	19,9
Cefotetan	1.6	2	0	0	0	0.7
Ampicillin–sulbactam	95.2	93.9	96.9	90.9	94.1	94.3
Piperacillin–tazobactam	7.9	8.2	11.1	12.7	14.7	11.1
Cefoperazone–sulbactam	0	0	14.5	20.4	22.7	18.6
Ertapenem	0	0	0	0	0	0
Imipenem	0	0	0	0	0	0
Meropenem	0	0	0	0	0	0
Amikacin	23.3	21.3	11.1	5.8	11.7	14.5
Gentamicin	52.4	51	62.5	61.8	58.8	57.5
Ciprofloxacin	47.6	46.9	48.4	29	30.9	40.5
Minocycline	55.9	55	56.5	56.6	56.9	56.7
Tigecycline	0	0	0	0	0	0

Abbreviation: ESBL, extended-spectrum β-lactamase.