Table 3.
Baseline characteristics of the 15,000 simulated patients of the model compared with the patients who participated in the DYNAGITO trial
| Model (15,000 sampled patients) | DYNAGITO trial (tiotropium arm) | |
|---|---|---|
| Female, % | 25.4 | 27.9 |
| Age (years) | 64.0 | 66.3 |
| FEV1 (L) | 1.19 | 1.20 |
| FEV1% predicted | 42 | 44 |
| Low BMI (<21 kg/m2), % | 18.1 | 18.3a |
| Smokers, % | 37.7 | 37.5 |
| Pack-years | 42.8 | 44.7 |
| ICS users, % | 62.8 | 70.1 |
| Severe exacerbations in previous year, % | 28.7 | 27.4 |
| SGRQ total score (points) | 47.5 | 47.4 |
Note:
a
Approximated based on the mean BMI + SD.
Abbreviations: BMI, body mass index; ICS, inhaled corticosteroid; SGRQ, St George’s Respiratory Questionnaire.